4 edition of Mammalian genetics and cancer found in the catalog.
Includes bibliographical references and index.
|Statement||editor, Elizabeth S. Russell.|
|Series||Progress in clinical and biological research ;, v. 45|
|Contributions||Russell, Elizabeth Shull, 1913-, Jackson Laboratory (Bar Harbor, Me.)|
|LC Classifications||RC268.4 .M35 1981|
|The Physical Object|
|Pagination||xiv, 327 p. :|
|Number of Pages||327|
|LC Control Number||80027531|
This book summarizes the current state of cancer genetics in clinical practice and effectively captures the excitement in this fast-moving field. It clearly demonstrates how genetics can now be applied to clinical oncology and is a harbinger of things to come for all areas of medical practice. Reviewed by John Bell, D.M. The Jackson Laboratory for Mammalian Genetics Bar Harbor, Maine The Jackson Laboratory's campus in Bar Harbor encompasses acres, with 68 buildings and 1 million square feet of space, and is nestled between the Gulf of Maine and the mountains of Acadia National Park, one mile from downtown Bar Harbor.
DNA methylation plays crucial roles in the regulation of chromatin structure and gene expression and is essential for mammalian development. Aberrant changes in DNA methylation levels and patterns are associated with various human diseases, including cancer . The life of the author, Chinese-born, T. C. Hsu, has been a romantic and color ful one, and he is himself a unique personality, so that his book is a very unusual blend of reminiscences, history of his special field (which has transformed human genetics) and wise comments on the mistakes made along the way.
Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest . David E. Malarkey, Robert R. Maronpot, in Haschek and Rousseaux's Handbook of Toxicologic Pathology (Third Edition), Somatic Mutation Theory. There is strong evidence that a critical step in carcinogenesis is a structural alteration occurring in the genetic machinery of a somatic cell. This appears to be true whether the active agent is a chemical or ionizing .
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Focused on the altered genes and pathways that cause the growth of the most common tumors, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff.
For students with a general interest in cancer, this book Cited by: Mammalian Development and Human Cancer: from the Phage Group to the Genetics of Intestinal Cancer, p In Cooper G, Temin R, Sugden B (ed), The DNA Provirus.
ASM Press, Washington, DC. doi: /ch8Cited by: 1. Genre/Form: Conference papers and proceedings Congress Congresses: Additional Physical Format: Online version: Mammalian genetics and cancer.
New York: A.R. Liss, © Buy Proceedings: Symposium on 25 Years of Progress in Mammalian Genetics and Cancer. on FREE SHIPPING on Mammalian genetics and cancer book orders. Genomics has experienced a dramatic development during the last years.
Data from mammalian genomes such as the human, mouse and rat have already been published, while others such as the dog, cattle and chimpanzee will soon follow.
This book summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes. This book explores possible genetic treatments that can suppress cancer cells that have formed tumors and it presents the details of the isolation and characterization of new human cancer genes that have recently been identified.
Molecular Genetics of Cancer, 2E is an essential book for anyone involved in cancer research and the search for a cure. Purchase Molecular Genetics of Mammalian Cells, Volume - 1st Edition. Print Book & E-Book. ISBNCancer genetics is a field of daunting breadth and depth. The literature describes hundreds of genes and genetic alterations that are variably associated with again as many disease states and risk factors.
Integrating these disparate pieces of highly specialized information is. Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics.
Emphasis is placed on the molecular bases of drug action, both applied and experimental. Vol GeneTherapy, features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and. Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics.
While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key. The book opens with a chapter on the history of the molecular approach to the thalassemias, among the most common and severe of all human genetic diseases.
Separate chapters follow covering the history and current state of the fragile X syndrome; the mechanisms of hepatitis B viral gene expression, its relation to liver cancer, and its. Hannon, G. et al. MaRX: an approach to genetics in mammalian cells.
Science– (). CAS PubMed Google Scholar. Mammalian Genome is the official journal of the International Mammalian Genome Society. Focuses on experimental, theoretical, and technical aspects of genomics and genetics in mouse, human, and other species; Offers original papers that present novel findings in all areas of mammalian genetic research as well as reviews on areas of topical interest.
Patients with non-small cell lung cancer (NSLC) are often treated with DNA cross-linking platinum therapeutic compounds such as cisplatin, carboplatin or oxaliplatin. NSCLC is the leading cause of cancer deaths worldwide, and almost 70% of patients with NSCLC have locally advanced or metastatic disease at diagnosis.
He has published more than refereed papers in leading genetic journals and edited eleven books so far. This includes the series of books on mammalian genetics, which is currently going into a second edition.
His most recent book, Genetics and Randomness, was published in He is affiliated with the University of New England, s: 3. Zebrafish (Danio rerio) is a valuable non-mammalian vertebrate model widely used to study development and disease, including more recently cancer.
The evolutionary conservation of cancer-related programs between human and zebrafish is striking and allows extrapolation of research outcomes obtained in fish back to humans. Zebrafish has gained attention as a robust model for cancer. Get this from a library.
Proceedings: Symposium on 25 Years of Progress in Mammalian Genetics and Cancer, Roscoe B. Jackson Memorial Laboratory, Bar Harbor, Maine, June 27 to 30, [Elizabeth Shull Russell; Roscoe B.
Jackson Memorial Laboratory.;]. Cancer is both a genetic and an epigenetic disease. The diverse field of epigenetics has rapidly added to the understanding of oncogenesis and has facilitated the development of novel therapeutic drugs, and will potentially generate new methods to.
Translational studies using mammalian and non-mammalian models, and cell lines are included. The Cancer Genetics [CG] Study Section reviews applications related to the identification and characterization of target genes involved in tumor pathogenesis using global scale genomic and epigenomic approaches.
Gene Expression and Regulation in Mammalian Cells - Transcription From General Aspects. Edited by: Fumiaki Uchiumi. ISBNeISBNPDF ISBNPublished. Additional funding was provided by the Integrated Cancer Biology Program grant 1-UCA to D.A.L.
and M.T.H. A mammalian functional-genetic approach to characterizing cancer therapeutics.Genetic Changes and Cancer. Cancer is a genetic disease—that is, cancer is caused by certain changes to genes that control the way our cells function, especially how they grow and divide.
Genes carry the instructions to make proteins, which do much of the work in our n gene changes can cause cells to evade normal growth controls and become cancer.Full text Full text is available as a scanned copy of the original print version.
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